Dr Jim Rybacki's blog

American Heart scientific sessions and ALN-PCSsc, an RNAi Investigational Agent

I'm here at the 2015 American Heart Association Scientific Sessions and will bring you many many key points in the next 2 weeks. This meeting is filled with science and results and fascinating new medicines, SPRINT to new blood pressure goals, measurements such as TIMI and DAPT risk scores and so much more.

Did you get your flu vaccination yet? How about today?

beach scene There you were sitting on the beach. Where does the time go? Summer is over now and the leaves are starting to fall. I got my flu shot yesterday. How about you?

PDUFA day for evolocumab (Repatha) at the US FDA

surfer The first PCSK9 inhibitor approved in the world stands before the FDA today for possible US approval. Evolocumab (brand name is Repatha) was approved by the European Medicines Agency (EMA) May 22, 2015.

Shock at the Pharmacy Drive Up Window

Something is fishy  After lunch I stopped at a large Pharmacy chain to hand in 2 written prescriptions and to ask for a refill on one of the other prescriptions that my doctor had just called in. Three prescriptions, nothing unusual. (little did I know, something was fishy).

Methaqualone (Quaaludes) in the news again

Qaaludes have been thrust in the media again. Apparently information surfaced on CNN today regarding a deposition where the comedian Bill Cosby admitted under oath that he had obtained 7 prescriptions for Quaaludes-(methaqualone + antihistamine) with the intent to use them to get sexual intercourse per CNN.

Flibanserin fine by FDA committee, with a risk plan recommendation

An FDA advisory panel voted 18 to 6 in favor of approval of the Sprout Pharmaceuticals medicine called flibanserin (Girosa). The FDA usually follows the recommendations of the expert panels, but is not bound to do so.

Flibanserin folly or real female benefit for decreased sexual desire?

bicycle on beach Flibanserin (Fluh BAN ser ihn) for female sexual desire has been a controversial medicine, possibly because of the way it works (increasing blood flow to the genitals), but more broadly, because of the condition (hypoactive sexual desire disorder- HSDD) that the medicine might tr

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